In Vitro Diagnostics2022-08-19T14:05:53-04:00

In Vitro Diagnostics.

Ensure and validate at every step of the way.

Immunoassays provide a fast, simple, and cost-effective method of detection with high sensitivity and specificity. They exploit the properties of antibodies to identify disease biomarkers, drugs, and other analytes. Without a secure stream of validated mAbs, IVD developers and manufacturers risk nonspecific binding, batch variability, or loss of supply – leading to wasted time and resources or project abandonment.

Sequencing the protein of the antibody reagent in parallel to assessing its affinity and specificity facilitates the development of reliable kits and immunoreagents securing research and manufacturing reproducibility. Obtaining protein sequences also enable recombinant expression, yielding consistent batches with predictable biological activity. Next generation protein sequencing (NGPS) can also help avoid issues with mAbs stemming from cell line drift, gene loss, and gene mutations.

Webinar

Rational Antibody Design and Engineering with Next Generation Protein Sequencing

Oct 20, 11 am EST

Services for In Vitro Diagnostic Developers.

We support IVD companies and reagent manufacturers in all stages of antibody selection, development, characterization, validation and production. Contact us to discover how we can help with your IVD application.

Antibody Sequencing & Discovery Services.

de novo mAb Sequencing

Safeguard the sequence of high-demand immunoreagents for posterity, and/or IP, or to meet regulatory guidelines. Secure your antibody supply chain.
Explore REmAb

Fast ADA Assays

Custom anti-drug antibody (ADA) control reagents assess clinical safety and efficacy in biologics and biosimilars. ADAs derived from the circulating polyclonal antibodies (pAb) can be easily derived by polyclonal antibody sequencing.
Explore REpAb

Quality Control and Troubleshooting

Routinely certify immunoreagents by confirming the expected sequence for the highest quality with minimal troubleshooting.
Explore MATCHmAb

Binding Kinetics

Assess and validate antibody binding affinities, on-rates and off-rates, ensuring reagents are fit-for-purpose in your assay and adhering to quality by design principles.
Explore SPR

Epitope Mapping

Assess and validate antigenic epitopes of antibody products, ensuring the correct antibody targets and increased sensitivity of your assay through epitopic diversity.
Explore HDX-MS

Recombinant Expression

Obtain the protein sequence and recombinantly express the product in a streamlined workflow, ensuring batch-to-batch consistency.
Explore Antibody Expression

Application Publications.

Next Generation Protein Sequencing in Veterinary Medicine and Industry

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Since 2006, the One Health Initiative (OHI)’s goal has been to demonstrate the inextricable link between humans, animals, and the environment. Certainly, the current global pandemic is a great testament to the ties between climate change, humans, and animals that OHI has been working to highlight. The rise of other zoonotic diseases (e.g., Hendra, and Nipah viruses) not only directly affect humans through disease transmission but may also result in deep impacts to the food supply

“The protein sequence allowed us to control the antibody, affinity maturation, and do large production. Being able to produce 20mg of Ab is big advantage.”

Talk to Our Scientists.

We Have Sequenced 6000+ Antibodies and We Are Eager to Help You.

Through next generation protein sequencing, Rapid Novor enables reliable discovery and development of novel reagents, diagnostics, and therapeutics. Thanks to our Next Generation Protein Sequencing and antibody discovery services, researchers have furthered thousands of projects, patented antibody therapeutics, and developed the first recombinant polyclonal antibody diagnostics.

Talk to Our Scientists.

We Have Sequenced 6000+ Antibodies and We Are Eager to Help You.

Through next generation protein sequencing, Rapid Novor enables timely and reliable discovery and development of novel reagents, diagnostics, and therapeutics. Thanks to our Next Generation Protein Sequencing and antibody discovery services, researchers have furthered thousands of projects, patented antibody therapeutics, and ran the first recombinant polyclonal antibody diagnostics

Talk to our scientists. We have sequenced over 6000 antibodies and we are eager to help you.