Written by: Jenna Kerry, MSc Published: September 17, 2024 Contents Introduction Agonistic Antibody Mechanism of Action Agonistic Antibody Development Challenges Optimizing Agonistic Antibodies Agonistic Antibody Development Introduction In the last decade, immunotherapy has rapidly transformed treatments for cancer, autoimmune disorders, and infectious diseases. While the [...]
Written by: Jenna Kerry, MSc Published: August 14, 2024 Contents What are Antagonistic Antibodies? How do Antagonistic Antibodies Work? Antagonistic Antibody Opportunities Antagonistic Antibody Obstacles Antibody Discovery Platform for Antagonistic Antibodies What are Antagonistic Antibodies? Antagonistic antibodies are a monoclonal antibody that bind to and [...]
Written by: Jenna Kerry, MSc Published: August 1, 2024 Contents Introduction Disulfide Bond Structure and Function in Monoclonal Antibodies Disulfide Scrambling in Monoclonal Antibodies Impact of Disulfide Bonds on Monoclonal Antibodies Strategies to Prevent Disulfide Scrambling in Monoclonal Antibodies Disulfide Bond Analysis for Monoclonal Antibodies Introduction [...]
Written by: Jenna Kerry, MSc Published: June 10, 2024 Contents Introduction Advantages of Recombinant Antibody Cocktails Recombinant Antibody Cocktail Formats Engineering Recombinant Antibody Cocktails Production of Recombinant Antibody Cocktails Recombinant Antibody Cocktail Applications Generate Antibody Cocktails with De Novo Antibody Sequencing Service Introduction Recombinant antibody [...]
Written by: Jenna Kerry, MSc Published: May 1, 2024 Contents What are Autoantibodies? How are Autoantibodies Produced? How do Autoantibodies Become Pathogenic? Triggers for Pathogenic Autoantibodies Autoantibodies in Diagnosis and Treatment Autoantigen Discovery and Characterization Gaining Insight into Autoantibodies What Are Autoantibodies? Autoantibodies are a [...]
Written by: Jenna Kerry, MSc Published: March 5, 2024 Contents Introduction to Flow Cytometry Understanding Flow Cytometry Interpreting Flow Cytometry Data Antibody Selection for Flow Cytometry Antibody Validation for Flow Cytometry Beyond Binding Assays Introduction to Flow Cytometry Flow cytometry is used by a wide [...]
Written by: Jenna Kerry, MSc Published: February 2, 2024 Contents Introduction Recombinant Expression Systems Recombinant Expression of Polyclonal Antibodies Rapid Novor's Services Introduction Once antibody discovery, lead selection, and characterization is complete, researchers have a range of expression systems to choose from to produce the antibody [...]
Written by: Jenna Kerry, MSc Published: November 29, 2023 Contents Introduction Nanobody Structure Generation and Production Therapeutic and Diagnostic Applications Nanobody De Novo Sequencing Introduction Nanobodies, also known as single-domain antibodies or VHHs, are derived from the immune systems of camelids and are heavy-chain-only antibodies. Despite [...]