Cell Line Development2022-11-15T15:26:29-05:00

Cell Line Development.

Optimize Cell Line Development Workflows for High-Quality Biologics.

The development of stable cell lines and host-cell systems is crucial for the production of recombinant proteins and complex biologics; however, cell line development is a time-consuming process with challenges in every stage of the workflow. Advancements in analytical tools are being made to overcome challenges faced by cell line developers and engineers. Next generation protein sequencing (NGPS) and other MS-based proteomics techniques allows for:

  1. High-throughput screening and validation of clone pools
  2. Identification and characterization of protein product variations for rational protein engineering and/or cell line engineering
  3. Downstream product analysis, ensuring efficacy and quality of the protein product

Webinar

Alpaca Antibody Showdown – Selecting Specific Monoclonal Antibodies by SPR

Nov 30, 11 am EST

Services for Cell Line Development.

We support the workflows for cell line development at all stages. Contact Us to discover how we can help with your cell line development application.

Antibody Sequencing & Discovery Services.

Cell Pool Screening and Validation

Antibody verification by real-time peptide mapping. Antibody sequence confirmation service for reproducibility.
Explore MATCHmAb

Binding Kinetics

Characterize the binding properties of expressed antibody products to target antigens.
Explore SPR Analysis

Epitope Mapping

Characterize linear, conformational, or structural epitopes for expressed antibody products, and identify antibody-antigen binding sites.
Explore HDX-MS

Protein Engineering and Expression

Obtain sequences of expressed protein products for strategic protein engineering and downstream expression.
Explore MATCHmAb

Application Publications.

Antibody Validation and its Use Cases

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Antibodies are used in a variety of ways in academia and industry, from tools to therapeutics. Because antibodies are produced using live processes, which are naturally error-prone, validation is required from time to time. Furthermore, to develop biological therapeutics, the protein sequence must be confirmed as part of the regulatory process.

“We’re focused on coupling cytokines with a highly engineered VHVL of an antibody. So by sequencing the antibodies with Rapid Novor we are able to pull out the CDR to graft them into our platform and test in vitro and in vivo.”

Pavel Khrimian – Co-founder and CBO, Deka Biosciences

Talk to Our Scientists.

We Have Sequenced 7000+ Antibodies and We Are Eager to Help You.

Through next generation protein sequencing, Rapid Novor enables reliable discovery and development of novel reagents, diagnostics, and therapeutics. Thanks to our Next Generation Protein Sequencing and antibody discovery services, researchers have furthered thousands of projects, patented antibody therapeutics, and developed the first recombinant polyclonal antibody diagnostics.

Talk to Our Scientists.

We Have Sequenced 6000+ Antibodies and We Are Eager to Help You.

Through next generation protein sequencing, Rapid Novor enables timely and reliable discovery and development of novel reagents, diagnostics, and therapeutics. Thanks to our Next Generation Protein Sequencing and antibody discovery services, researchers have furthered thousands of projects, patented antibody therapeutics, and ran the first recombinant polyclonal antibody diagnostics

Talk to our scientists. We have sequenced over 6000 antibodies and we are eager to help you.