Antibody-Antigen Interaction Analysis by SPR.

Our binding kinetics services can determine the binding affinity, on-rate and off- rate (Kon, Koff and KD) for antibody-antigen interaction. Full kinetic profiling using our expertise in SPR for antibodies.

Antibody Binding Experts.

Rapid Novor has been supporting antibody therapeutic, diagnostic and reagent development since 2015. To date we have completed 6000+ successful projects. Our scientists have extensive experience in optimizing the analysis for your specific antigen.

Antibody Binding Experts.

Rapid Novor has been supporting antibody therapeutic, diagnostic and reagent development since 2015. To date we have completed 6000+ successful projects. Our scientists have extensive experience in optimizing the analysis for your specific antigen.

Complex SPR, Full Kinetic Profile.

We can work with antibodies and antibody fragments, fab, scvf. We can work with mAbs or pAbs. We can work with peptide antigens and large complex protein antigens, even protein complexes.

How Rapid SPR Service Works.

Method

Our method for label free evaluation of antibody-antigen binding relies on a Surface Plasmon Resonance technology from Nicoya called OpenSPR. This nanotechnology-based SPR platform enables immobilization of binding partners in both orientations with low levels for bulk shift even in most complex buffers. Combined with our expertise in antibody interactions, this results in high sensitivity and the lowest noise even in complex analytes.

antibody antigen bidning analysis through SPR workflow infographic

Turn Around Time

Single Ag-Ab pair: 2-3 weeks

Rush: 1 week*

Binning/screening: inquire

* sample dependent

Requirements

– Antibody (100 μg, >90% purity, monoclonal)

– Antigen (at least 100 μg, >90% purity)

Any standard buffer. Inquire about serum analysis.

Deliverables

Full kinetic profile including Kon, Koff and KD for each antibody-antigen pair

Pricing.

Per sample fees, setup and optimization costs depend on project requirements. Please inquire.

Volume pricing discounts available

Talk to Our Scientists.

We Have Sequenced 6000+ Antibodies and We Are Eager to Help You.

Through next generation protein sequencing, Rapid Novor enables reliable discovery and development of novel reagents, diagnostics, and therapeutics. Thanks to our Next Generation Protein Sequencing and antibody discovery services, researchers have furthered thousands of projects, patented antibody therapeutics, and developed the first recombinant polyclonal antibody diagnostics.

We Have Sequenced 6000+ Antibodies and We Are Eager to Help You.

Through next generation protein sequencing, Rapid Novor enables timely and reliable discovery and development of novel reagents, diagnostics, and therapeutics. Thanks to our Next Generation Protein Sequencing and antibody discovery services, researchers have furthered thousands of projects, patented antibody therapeutics, and ran the first recombinant polyclonal antibody diagnostics

Talk to our scientists. We have sequenced over 5000 antibodies and we are eager to help you.