Engineering and Kinetic Analysis of TNFɑ Inhibitory Nanobodies via SPR
To develop robust mAb biologics, it is vital to fully characterize the protein, including its primary sequence, mutations, and important post-translational modifications
October 2025
March 2024
Antibodies in Flow Cytometry – The Key to Success
Written by: Jenna Kerry, MSc Published: March 5, 2024 Contents Introduction to Flow Cytometry Understanding Flow Cytometry Interpreting Flow Cytometry Data Antibody Selection for Flow Cytometry Antibody Validation for Flow Cytometry Beyond Binding Assays Introduction to Flow Cytometry Flow cytometry is used by a wide [...]
November 2023
Nanobody Sequencing: Unlocking Therapeutic Potential
Written by: Jenna Kerry, MSc Published: November 29, 2023 Contents Introduction Nanobody Structure Generation and Production Therapeutic and Diagnostic Applications Nanobody De Novo Sequencing Introduction Nanobodies, also known as single-domain antibodies or VHHs, are derived from the immune systems of camelids and are heavy-chain-only antibodies. [...]
February 2023
Nanobody Lead Optimization with Epitope Mapping and Binning
In this webinar, you will learn: How Rapid Novor’s de novo polyclonal sequencing platform REpAb® can accelerate any nanobody development pipeline How SPR and HDX-MS integrate into an antibody discovery and development workflow How to choose optimal lead candidates with SPR and HDX-MS How epitopes can be characterized using SPR and HDX-MS [...]
October 2022
Selecting Specific Monoclonal Antibodies by SPR – Alpaca Antibody Showdown
In this SPR webinar, you will learn: How SPR works and its unique advantages for kinetic analysis of antibody-antigen interactions Applications of SPR in antibody discovery Functionality of SPR in antibody characterization Abstract Due to their ability to bind biomolecules specifically and tightly, antibodies are highly sought [...]
February 2022
Camelid Antibodies and Nanobodies
Written by: Yuning Wang, PhD Updated: January 18, 2023 (Published: January 21, 2022) Contents Discovery of Camelid Antibodies What are Camelid Antibodies? Structure of Camelid Antibodies and Nanobodies Advantages of Camelid Antibodies and Nanobodies Camelid Antibodies and Nanobodies for Therapeutic and Research Applications How are Camelid Antibodies [...]