Developing CAR-T Therapies Against Novel Cancer Antigens
To develop robust mAb biologics, it is vital to fully characterize the protein, including its primary sequence, mutations, and important post-translational modifications
July 2025
February 2025
Major Histocompatibility Complex Therapeutic Applications
Written by: Jenna Kerry, MSc Published: February 26, 2025 Contents Introduction MHC Cancer Therapeutics MHC Autoimmune Disease Therapeutics MHC Infectious Disease Therapeutics MHC Therapeutics Computational Methods Immunopeptidomics Accelerating Immunopeptidomics with Rapid Novor's AI Algorithm Introduction The Major Histocompatibility Complex (MHC) is a key player in [...]
Major Histocompatibility Complex
Written by: Jenna Kerry, MSc Published: February 13, 2025 Contents What is the Major Histocompatibility Complex? Major Histocompatibility Complex Structure and Function Major Histocompatibility Complex Adaptability and Evolution Major Histocompatibility Dysfunction Major Histocompatibility Complex and Immunopeptidomics Sequencing with Rapid Novor What is the Major Histocompatibility Complex? [...]
December 2024
Phage Display Antibody Discovery
Written by: Jenna Kerry, MSc Published: December 20, 2024 Contents What is Phage Display? How Does Phage Display Work? Phage Display Technology Advantages Phage Display Technology Limitations The Future of Phage Display Technology Overcoming Limitations of Phage Display Antibody Discovery What is Phage Display? Over [...]
November 2024
Antibody Humanization Strategies, Challenges, and Innovations
Written by: Jenna Kerry, MSc Published: November 6, 2024 Contents Why Humanize Antibodies? What is Antibody Humanization? Antibody Humanization Techniques Current Challenges of Antibody Humanization The Future of Human Antibody Therapeutics Fully Human Antibody Discovery / Human Antibody Discovery From Human Serum Why Humanize Antibodies? [...]
September 2024
Agonist Antibody Challenges and Optimization
Written by: Jenna Kerry, MSc Published: September 17, 2024 Contents Introduction Agonistic Antibody Mechanism of Action Agonistic Antibody Development Challenges Optimizing Agonistic Antibodies Agonistic Antibody Development Introduction In the last decade, immunotherapy has rapidly transformed treatments for cancer, autoimmune disorders, and infectious diseases. While the [...]
August 2022
What are Polyclonal Antibodies?
Written by: Genya Gorshtein, MSc Published: August 18, 2022 Contents Introduction How are Polyclonal Antibodies Produced? Applications of Polyclonal Antibodies Challenges of Polyclonal Antibodies De Novo Polyclonal Antibody Sequencing Introduction Polyclonal antibodies (pAbs) are a heterogeneous mix of antibodies derived from B cells in the [...]