Synthetic Antigens Enable CAR-T Cell Targeting of Solid Tumors
To develop robust mAb biologics, it is vital to fully characterize the protein, including its primary sequence, mutations, and important post-translational modifications
July 2025
Developing CAR-T Therapies Against Novel Cancer Antigens
To develop robust mAb biologics, it is vital to fully characterize the protein, including its primary sequence, mutations, and important post-translational modifications
February 2025
Antibody Tools for Target Identification and Validation
Written by: Genya Gorshtein, MSc Published: February 10, 2025 Contents Introduction Process of Target Identification and Validation Antibodies as Tools for Target ID and Validation Experiments Custom Antibody Development for Target Validation Custom Antibody Services with Rapid Novor Introduction Successful drug discovery begins with [...]
October 2024
Trick or Treat: Unmasking Antibody Reproducibility in Life Sciences
In this webinar, you will learn: How mAb irreproducibility could unknowingly impact your research outcomes Proven strategies to mitigate reproducibility risks when using research reagents The role of antibody sequencing in ensuring reproducibility with mAbs Rapid, cost-effective sequence confirmation for routine applications The next frontier: polyclonal antibody sequencing and recombinant pAbs [...]
May 2024
Autoantibodies: Natural and Pathogenic
Written by: Jenna Kerry, MSc Published: May 1, 2024 Contents What are Autoantibodies? How are Autoantibodies Produced? How do Autoantibodies Become Pathogenic? Triggers for Pathogenic Autoantibodies Autoantibodies in Diagnosis and Treatment Autoantigen Discovery and Characterization Gaining Insight into Autoantibodies What Are Autoantibodies? Autoantibodies are a [...]
June 2023
Tackling Reproducibility in Life Sciences with Protein Sequencing
Written by: Genya Gorshtein, MSc Published: May 9, 2023 Contents Introduction Hybridoma Instability Leads to mAb Irreproducibility Batch-to-Batch Variation in Polyclonal Antibodies Antibody Sequencing and Recombinant Expression Ensures Reproducible Antibody Reagents Generating Reproducible Reagents with Rapid Novor Introduction Antibodies (Abs) are indispensable tools in [...]
May 2023
Rational Antibody Design and Engineering with Next Generation Protein Sequencing
In this webinar, you will learn: A strategy for generating recombinant mAbs and antibody derivatives directed towards antigens involved in mitotic cell division Methods for antibody engineering and customization, species switching, and construction of antibody fragments How Next Generation Protein Sequencing (NGPS) works Applications of NGPS to aid engineering and recombinant production of [...]
April 2022
Generation and Diversification of Recombinant Monoclonal Antibodies
Monoclonal antibodies are essential reagents and research tools. They are commonly generated and produced in hybridoma cells and are expected to be highly consistent. However, the instability and fragility of hybridoma cells can cause unwanted mutations, additional chains, and permanent loss of important antibodies. On the other hand, the lack of standardization validation for commercial antibodies often keeps researchers in the dark leading to the reproducibility crisis.
August 2021
Antibody Validation and its Use Cases
Antibodies are used in a variety of ways in academia and industry, from tools to therapeutics. Because antibodies are produced using live processes, which are naturally error-prone, validation is required from time to time. Furthermore, to develop biological therapeutics, the protein sequence must be confirmed as part of the regulatory process.