Surface plasmon resonance Archives

Antibody Affinity and Avidity – The Strength of a Single Interaction Versus a Multivalent Interaction

Genya Gorshtein2023-05-25T10:20:23-04:00January 9th, 2023|Articles|

Written by: Genya Gorshtein, MSc Published: January 6, 2023 Contents Introduction What is Affinity? What is Avidity? Measuring Affinity and Avidity: ELISA or SPR? Measuring Affinity And Avidity For Biological Applications Affinity and Avidity Analysis via SPR with Rapid Novor Introduction Kinetics of antibody-antigen interactions [...]

Cell Specific Protein Degradation with Antibody Conjugated PROTACs

Genya Gorshtein2023-05-25T10:29:24-04:00December 2nd, 2022|Articles|

Written by: Genya Gorshtein, MSc Published: November 25, 2022 Contents Introduction General PROTAC Structure and Function Antibody-Conjugated PROTACs Developing AbPROTACs with De Novo Antibody Sequencing and Proteomics Introduction Small-molecule drug development is aimed at inhibiting disease-promoting protein function through occupancy-driven protein inhibition. A major caveat of [...]

January 2023

Antibody Affinity and Avidity – The Strength of a Single Interaction Versus a Multivalent Interaction

December 2022

Cell Specific Protein Degradation with Antibody Conjugated PROTACs

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