When Hybridomas Die: Recovering Critical Reagents with Antibody Sequencing
To develop robust mAb biologics, it is vital to fully characterize the protein, including its primary sequence, mutations, and important post-translational modifications
September 2025
October 2024
Trick or Treat: Unmasking Antibody Reproducibility in Life Sciences
In this webinar, you will learn: How mAb irreproducibility could unknowingly impact your research outcomes Proven strategies to mitigate reproducibility risks when using research reagents The role of antibody sequencing in ensuring reproducibility with mAbs Rapid, cost-effective sequence confirmation for routine applications The next frontier: polyclonal antibody sequencing and recombinant pAbs [...]
August 2024
Antagonistic Antibodies: Opportunities and Obstacles
Written by: Jenna Kerry, MSc Published: August 14, 2024 Contents What are Antagonistic Antibodies? How do Antagonistic Antibodies Work? Antagonistic Antibody Opportunities Antagonistic Antibody Obstacles Antibody Discovery Platform for Antagonistic Antibodies What are Antagonistic Antibodies? Antagonistic antibodies are a monoclonal antibody that bind to and [...]
Detecting and Preventing Disulfide Scrambling in Monoclonal Antibodies
Written by: Jenna Kerry, MSc Published: August 1, 2024 Contents Introduction Disulfide Bond Structure and Function in Monoclonal Antibodies Disulfide Scrambling in Monoclonal Antibodies Impact of Disulfide Bonds on Monoclonal Antibodies Strategies to Prevent Disulfide Scrambling in Monoclonal Antibodies Disulfide Bond Analysis for Monoclonal Antibodies Introduction [...]
June 2024
The Power of Recombinant Antibody Cocktails
Written by: Jenna Kerry, MSc Published: June 10, 2024 Contents Introduction Advantages of Recombinant Antibody Cocktails Recombinant Antibody Cocktail Formats Engineering Recombinant Antibody Cocktails Production of Recombinant Antibody Cocktails Recombinant Antibody Cocktail Applications Generate Antibody Cocktails with De Novo Antibody Sequencing Service Introduction Recombinant antibody [...]
August 2022
What are Polyclonal Antibodies?
Written by: Genya Gorshtein, MSc Published: August 18, 2022 Contents Introduction How are Polyclonal Antibodies Produced? Applications of Polyclonal Antibodies Challenges of Polyclonal Antibodies De Novo Polyclonal Antibody Sequencing Introduction Polyclonal antibodies (pAbs) are a heterogeneous mix of antibodies derived from B cells in the [...]