August 2022

What are Polyclonal Antibodies?

2022-11-17T13:24:32-05:00August 18th, 2022|Articles|

Written by Genya Gorshtein, MSc August 18, 2022 Contents Introduction How are Polyclonal Antibodies Produced? Applications of Polyclonal Antibodies Challenges of Polyclonal Antibodies De Novo Polyclonal Antibody Sequencing Introduction Polyclonal antibodies (pAbs) are a heterogeneous mix of antibodies derived from B cells in the adaptive immune system. [...]

Structure and Function of Antibodies

2022-08-24T17:37:21-04:00August 10th, 2022|Articles|

Written by Genya Gorshtein, MSc August 10, 2022 Contents General Structure of Antibodies Fab and Fc Fragments Hinge Region CDR and FR Regions Antibody Structure Analysis Services General Structure of Antibodies Antibodies or immunoglobulins (Ig) maintain a common quaternary structure consisting of two identical heavy chains (HCs) and two [...]

July 2022

Protein Characterization by HDX-MS

2022-10-27T11:20:06-04:00July 26th, 2022|Articles|

Written by Vanessa Yoon Calvelo, PhD July 21, 2022 Contents Mass spectrometry-based approaches for structural analysis of proteins HDX-MS Applications for ‘Difficult’ Proteins HDX-MS – A powerful analytical technique for protein characterization Mass spectrometry-based approaches for structural analysis of proteins Characterization of proteins and protein complexes is [...]