May 2024

Ask Our Experts: Navigating Antibody Characterization through LC-MS

2024-07-12T09:51:00-04:00May 1st, 2024|Webinars|

In this webinar, you will… Learn the details of LC-MS based antibody characterization in early discovery and production pipelines Explore in-depth the analytical methodologies and strategies essential for comprehensive antibody characterization, covering post-translational modifications, glycan profiles, peptide mapping, and disulfide linkages Ask your burning questions and get expert guidance on navigating antibody [...]

February 2024

Antibody Production: A Guide to Choosing a Recombinant Expression System

2024-05-06T12:35:16-04:00February 2nd, 2024|Articles|

Written by: Jenna Kerry, MSc Published: February 2, 2024 Contents Introduction Recombinant Expression Systems Recombinant Expression of Polyclonal Antibodies Rapid Novor's Services Introduction Once antibody discovery, lead selection, and characterization is complete, researchers have a range of expression systems to choose from to produce the antibody [...]

October 2023

The Basics of Protein and Antibody Glycosylation

2024-06-13T16:40:40-04:00October 20th, 2023|Articles|

Written by: Genya Gorshtein, MSc Published: October 18, 2023 Contents Introduction Types of Glycans How are Proteins Glycosylated? Why are Proteins Glycosylated? Protein Glycosylation in the Immune System Importance of Understanding Glycan Profiles of Proteins Discover Glycan Sites and Profiles with Rapid Novor Introduction [...]

New Antibody Characterization Essentials from Discovery to Clinic

2024-04-24T10:34:49-04:00October 4th, 2023|Webinars|

In this webinar, you will learn: Workflows for antibody characterization that extend beyond the primary amino acid sequence How to leverage HDX-MS for epitope mapping and SPR for binding kinetics to understand the mechanism of action and maximize the effectiveness of your characterization efforts How to ensure high-quality antibody production with [...]

September 2023

Antibody Developability: Sequence and Structure Impacts Antibody Aggregation

2024-05-06T16:28:19-04:00September 12th, 2023|Articles|

Written by: Genya Gorshtein, MSc Published: September 12, 2023 Contents Introduction Mechanisms That Influence Protein Aggregation and Stability Sequence and Structural Characteristics That Impact Antibody Aggregation and Stability Engineered Antibody Formats Influence Protein Aggregation Strategies to Reduce Antibody Aggregation Propensity Improving Antibody Developability with Next Generation Protein Sequencing and Proteomics [...]