Engineering and Kinetic Analysis of TNFɑ Inhibitory Nanobodies via SPR
To develop robust mAb biologics, it is vital to fully characterize the protein, including its primary sequence, mutations, and important post-translational modifications
October 2025
June 2025
Biparatopic Antibodies
Written by: Genya Gorshtein, MSc Published: June 13, 2025 Contents Introduction What Are Biparatopic Antibodies? How Are Biparatopic Antibodies Engineered? Biparatopic vs. Bispecific Antibodies: What’s the Difference? Engineering Biparatopic Antibodies with Rapid Novor Introduction Biparatopic antibodies are a subclass of bispecific antibodies that bind [...]
December 2024
Phage Display Antibody Discovery
Written by: Jenna Kerry, MSc Published: December 20, 2024 Contents What is Phage Display? How Does Phage Display Work? Phage Display Technology Advantages Phage Display Technology Limitations The Future of Phage Display Technology Overcoming Limitations of Phage Display Antibody Discovery What is Phage Display? Over [...]
November 2024
NOT gated T cells that selectively target EGFR and other widely expressed tumor antigens
To develop robust mAb biologics, it is vital to fully characterize the protein, including its primary sequence, mutations, and important post-translational modifications
Antibody Humanization Strategies, Challenges, and Innovations
Written by: Jenna Kerry, MSc Published: November 6, 2024 Contents Why Humanize Antibodies? What is Antibody Humanization? Antibody Humanization Techniques Current Challenges of Antibody Humanization The Future of Human Antibody Therapeutics Fully Human Antibody Discovery / Human Antibody Discovery From Human Serum Why Humanize Antibodies? [...]
October 2024
De Novo Protein Sequencing of Antibodies for Identification of Neutralizing Antibodies in Human Plasma Post SARS-CoV-2 Vaccination
To develop robust mAb biologics, it is vital to fully characterize the protein, including its primary sequence, mutations, and important post-translational modifications
September 2024
Agonist Antibody Challenges and Optimization
Written by: Jenna Kerry, MSc Published: September 17, 2024 Contents Introduction Agonistic Antibody Mechanism of Action Agonistic Antibody Development Challenges Optimizing Agonistic Antibodies Agonistic Antibody Development Introduction In the last decade, immunotherapy has rapidly transformed treatments for cancer, autoimmune disorders, and infectious diseases. While the [...]
July 2024
DAR Analysis of TRBC1-Targeting Antibody–Drug Conjugates
To develop robust mAb biologics, it is vital to fully characterize the protein, including its primary sequence, mutations, and important post-translational modifications
May 2024
Ask Our Experts: Navigating Antibody Characterization through LC-MS
In this webinar, you will… Learn the details of LC-MS based antibody characterization in early discovery and production pipelines Explore in-depth the analytical methodologies and strategies essential for comprehensive antibody characterization, covering post-translational modifications, glycan profiles, peptide mapping, and disulfide linkages Ask your burning questions and get expert guidance on navigating antibody [...]