Unlocking the Dark Metaproteome: De Novo Protein Sequencing Reveals Hidden Microbial Proteins and Druggable Targets
We are proud to be part of a newly published peer-reviewed study in Nature Communications. By combining PASEF-enabled mass spectrometry with de novo protein sequencing, the team greatly improved sensitivity and detection in complex microbiomes. The approach introduces the concept of a "druggable metaproteome", offering a new framework to advance microbiome research and develop [...]