In this webinar, you will learn: Six frequently missed observations with critical impacts on antibody validation, hit selection and candidate characterization efforts. Antibody biochemistry tips for design of SPR, and mass spectrometry-based epitope mapping workflows. Characterizing Antibody Epitopes: What the Experts Say You’re Missing In this webinar, we [...]
In this webinar, you will learn:About paratope-centered patenting as a way to build stronger, structurally defined claims that withstand enablement and design-around challenges.How evolving case law, USPTO guidance, and antibody characterization tools can open new avenues for securing robust protection for therapeutic antibodies.Experimental strategies for resolving epitope and paratope including efficiently permutating and screening [...]
Written by: Genya Gorshtein, MSc Published: July 17, 2025 Contents Introduction What is a Linear Epitope? What is a Conformational Epitope? Antigen Design for Antibody Discovery: Linear vs. Conformational Epitope Considerations Protein Interaction Analysis Service with HDX-MS Introduction Antibodies recognize specific regions on antigens [...]
Senior Scientist & Manager of HDX-MS Epitope Mapping Services Dr. Dominic Narang is a Senior Scientist & Manager of HDX-MS epitope mapping services at Rapid Novor, bringing over 7 years of experience in structural biology and mass spectrometry. He specializes in providing solutions to biotechnology and pharma companies for their drug discovery and [...]
Written by: Genya Gorshtein, MSc Published: October 16, 2024 Contents Introduction Epitope Mapping Methods Addressing the Limitations of HDX-MS for Epitope Mapping HDX-MS as a Stand Alone Method for Epitope Mapping Epitope Mapping with HDX-MS at Rapid Novor Introduction Understanding antibody-antigen interactions is critical [...]
In this webinar, you will learn: How AI and HDX-MS are applied in screening, epitope mapping, and selecting neutralizing antibodies against SARS-Cov-2. The predictive capabilities of AI computational modeling and its validation and refinement by high-resolution HDX-MS. How the integration of AI with HDX-MS informs antibody characterization for the accelerated development of therapeutic [...]
In this webinar, you will learn: How Rapid Novor’s de novo polyclonal sequencing platform REpAb® can accelerate any nanobody development pipeline How SPR and HDX-MS integrate into an antibody discovery and development workflow How to choose optimal lead candidates with SPR and HDX-MS How epitopes can be characterized using SPR and HDX-MS [...]