Written by: Genya Gorshtein, MSc Published: July 17, 2025 Contents Introduction What is a Linear Epitope? What is a Conformational Epitope? Antigen Design for Antibody Discovery: Linear vs. Conformational Epitope Considerations Protein Interaction Analysis Service with HDX-MS Introduction Antibodies recognize specific regions on antigens [...]
Senior Scientist & Manager of HDX-MS Epitope Mapping Services Dr. Dominic Narang is a Senior Scientist & Manager of HDX-MS epitope mapping services at Rapid Novor, bringing over 7 years of experience in structural biology and mass spectrometry. He specializes in providing solutions to biotechnology and pharma companies for their drug discovery and [...]
Written by: Genya Gorshtein, MSc Published: October 16, 2024 Contents Introduction Epitope Mapping Methods Addressing the Limitations of HDX-MS for Epitope Mapping HDX-MS as a Stand Alone Method for Epitope Mapping Epitope Mapping with HDX-MS at Rapid Novor Introduction Understanding antibody-antigen interactions is critical [...]
In this webinar, you will learn: How AI and HDX-MS are applied in screening, epitope mapping, and selecting neutralizing antibodies against SARS-Cov-2. The predictive capabilities of AI computational modeling and its validation and refinement by high-resolution HDX-MS. How the integration of AI with HDX-MS informs antibody characterization for the accelerated development of therapeutic [...]
In this webinar, you will learn: How Rapid Novor’s de novo polyclonal sequencing platform REpAb® can accelerate any nanobody development pipeline How SPR and HDX-MS integrate into an antibody discovery and development workflow How to choose optimal lead candidates with SPR and HDX-MS How epitopes can be characterized using SPR and HDX-MS [...]