In this webinar, you will learn: Low-density pMHC immobilization as a strategy to obtain valid monovalent affinity from a bivalent binder under limited antigen supply. Application of this SPR method to rank a panel of affinity-matured pMHC binders and select a lead candidate by monovalent affinity. Direct translation of SPR-based lead selection into [...]
In this webinar, you will learn: The challenges of developing biologics capable of crossing the blood-brain barrier (BBB) and emerging strategies for engineering BBB-penetrant therapeutics. Why multispecifics are an ideal vehicle for delivery of BBB therapeutics. How multispecifics targeting the BBB can be designed, validated and optimized for efficient transcytosis and TNF-α targeting [...]
In this webinar, you will learn: How to select the appropriate bispecific antibody format based on your target and functional intent. How to apply the various manufacturing and protein engineering approaches to overcome bispecific complexity. How high-confidence monoclonal antibody sequencing enables reproducible bispecific design. Building Bispecific Antibodies with Confidence Bispecific [...]
Written by: Genya Gorshtein, MSc Published: June 13, 2025 Contents Introduction What Are Biparatopic Antibodies? How Are Biparatopic Antibodies Engineered? Biparatopic vs. Bispecific Antibodies: What’s the Difference? Engineering Biparatopic Antibodies with Rapid Novor Introduction Biparatopic antibodies are a subclass of bispecific antibodies that bind [...]