August 2022

Moving Towards Biosimilar Drugs

2022-11-17T13:38:05-05:00August 4th, 2022|Articles|

Written by Vanessa Yoon Calvelo, PhD August 3, 2022 Contents What are Biosimilar Drugs? Why are Biosimilars Being Developed? Biosimilars are not the Equivalent of Generics Biosimilar Development Biosimilar Monoclonal Antibodies De Novo Protein Sequencing Solutions in Biosimilar Development What are Biosimilar Drugs? Biosimilar drugs, also known [...]

June 2022

Why do Post-Translational Modifications Matter?

2022-08-09T16:40:29-04:00June 14th, 2022|Articles|

Written by Vanessa Yoon Calvelo, PhD June 2, 2022 Contents What are post-translational modifications (PTMs)? Impact of PTMs Types of PTMs PTMs increase microheterogeneity of antibodies Characterization of PTMs by next generation protein sequencing What are Post-Translational Modifications? Post-translational modifications (PTMs) are processing events typically driven by [...]

Protein Structure and How to Study it

2022-06-10T10:22:08-04:00June 10th, 2022|Articles|

Written by Yuning Wang, PhD June 3, 2022 Contents Background Four levels of protein structure How are protein structures studied? Background Structural information provides a great deal of understanding of how a protein works, which can allow us to elucidate molecular mechanisms underlying human diseases. Rapidly developing [...]