January 2024

Modifying Antibody Functions Through Glycan Engineering

2024-06-13T16:39:42-04:00January 8th, 2024|Articles|

Written by: Genya Gorshtein, MSc Published: January 8, 2024 Contents Introduction Glycoengineering of Therapeutic mAbs Glycoengineering Methods Informed Glycan Engineering through LC-MS Glycan Analysis Introduction Glycosylation plays a crucial role in antibody functions, influencing protein folding, trafficking, stability, and half-life. While the glycosylated residue [...]

October 2023

The Basics of Protein and Antibody Glycosylation

2024-06-13T16:40:40-04:00October 20th, 2023|Articles|

Written by: Genya Gorshtein, MSc Published: October 18, 2023 Contents Introduction Types of Glycans How are Proteins Glycosylated? Why are Proteins Glycosylated? Protein Glycosylation in the Immune System Importance of Understanding Glycan Profiles of Proteins Discover Glycan Sites and Profiles with Rapid Novor Introduction [...]